W. H. Jung

The interplay between electron transport chain function and iron regulatory factors influences melanin formation in Cryptococcus neoformans

This paper investigates how mitochondrial electron transport chain function and iron regulatory factors influence melanin formation in Cryptococcus neoformans, revealing a link between mitochondrial dysfunction, redox homeostasis, and virulence.

Live Malassezia strains isolated from the mucosa of patients with ulcerative colitis

This study isolates and characterizes live Malassezia globosa strains from ulcerative colitis patients' intestinal mucosa, showing they exacerbate colitis in mice and exhibit hypoxia adaptation.

A novel virus alters gene expression and vacuolar morphology in Malassezia cells and induces a TLR3-mediated inflammatory immune response

The paper identifies a novel dsRNA virus in Malassezia restricta, shows it alters gene expression and cell morphology, and induces TLR3-mediated inflammation in dendritic cells.

The monothiol glutaredoxin Grx4 interacts with the Cryptococcus iron regulator Cir1 and regulates iron homeostasis and virulence in the Cryptococcus neoformans

This study identifies Grx4 as a binding partner of Cir1 in Cryptococcus neoformans, showing that Grx4 regulates iron homeostasis and virulence through its interaction with Cir1.

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

This study identifies Vps45's role in iron uptake, mitochondrial function, and virulence in Cryptococcus neoformans by analyzing a vps45 mutant's defects in trafficking, growth, and pathogenicity.