Author

M. Chand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. N. O'Toole· 2 shared A. Rambaut· 2 shared N. Groves· 2 shared N. Loman· 2 shared R. Myers· 2 shared A. Carabelli· 1 shared A. Price· 1 shared B. Gannon· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersEvolutionary Biology

A. N. O'Toole

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In Vitro Efficacy of Next Generation Dihydrotriazines and Biguanides Against Babesiosis and Malaria Parasites

P. Vydyam, M. Chand, S. Gihaz, I. Renard, G. D. Heffernan, L. R. Jacobus, D. P. Jacobus, K. W. Saionz, R. Shah, H.-M. Shieh, J. Terpinski, W. Zhao, E. Cornillot, C. Ben Mamoun

This study screens dihydrotriazines and biguanides against Babesia and Plasmodium parasites to identify effective antifolates with broad-spectrum activity and high therapeutic indices.

bioRxiv · Mar 20, 2024Microbiology

Putative APOBEC3 deaminase editing in MPXV as evidence for sustained human transmission since at least 2016.

A. N. O'Toole, R. Neher, N. Ndodo, V. Borges, B. Gannon, J. P. Gomes, N. Groves, D. J. King, D. Maloney, P. Lemey, K. Lewandowski, N. Loman, R. Myers, M. A. Suchard, M. Worobey, , A. Rambaut

The paper analyzes MPXV genomes to show evidence of APOBEC3 deaminase editing, suggesting sustained human transmission since 2016.

bioRxiv · Jan 23, 2023 · PreprintEvolutionary Biology

The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK

V. Hill, L. du Plessis, T. P. A. Peacock, D. Aggarwal, A. Carabelli, R. Colquhoun, N. Ellaby, E. Gallagher, N. Groves, B. Jackson, J. McCrone, A. N. O'Toole, A. Price, T. Sanderson, E. Scher, , A. Rambaut

This study investigates the origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 (Alpha) in the UK, finding that a chronically-infected immunocompetent individual likely drove its rapid mutation and spread.

bioRxiv · Mar 8, 2022Evolutionary Biology