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2 papers
Recent·Most cited
Z. Zhang, T. TeSlaa, X. Xu, X. Zeng, L. Yang, G. Xing, G. Tesz, M. Clasquin, J. Rabinowitz
The paper shows that liver generates NADPH for lipogenesis through serine catabolism, distinct from adipose which uses glucose and the pentose phosphate pathway.
bioRxiv · May 22, 2021Biochemistry
K. J. Corbit, C. G. Wilson, D. Lowe, J. L. Tran, N. B. Vera, M. Clasquin, A. N. Mattis, E. J. Weiss
This study shows that adipocyte JAK2 mediates GH-induced metabolic liver disease and progression to HCC in aged mice, highlighting adipocytes as key mediators.
bioRxiv · Jun 24, 2019 · PreprintPhysiology