Author

A. N. Mattis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. C. Duwaerts· 2 shared J. J. Maher· 2 shared A. A. Chang· 1 shared A. B. Molofsky· 1 shared A. L. Gan· 1 shared C. G. Wilson· 1 shared C. Her· 1 shared C. L. Her· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

C. C. Duwaerts

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Author profile →

4 papers

Recent·Most cited

Group 2 innate lymphoid cells constrain type 3/17 lymphocytes in shared stromal niches to restrict liver fibrosis

J. Sbierski-Kind, K. M. Cautivo, J. Wagner, M. W. Dahlgren, J. Nilsson, M. Krasilnikov, N. M. Mroz, C. O. Lizama, A. L. Gan, P. R. Matatia, M. T. Taruselli, A. A. Chang, S. Caryotakis, C. O'Leary, M. Kotas, , A. B. Molofsky

The paper investigates the role of IL-5+ lymphocytes and type 3/17 lymphocytes in liver fibrosis, showing their spatial relationship and cross-regulation in fibroblast niches.

bioRxiv · Apr 26, 2023 · PreprintImmunology

Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α

C. C. Duwaerts, K. Siao, R. K. Soon, C. Her, T. Iwawaki, K. Kohno, A. N. Mattis, J. J. Maher

This study shows that deleting XBP1 in hepatocytes causes liver injury in mice, which is due to excessive IRE1 activation rather than XBP1 loss itself.

Cell Death & Differentiation · Nov 20, 2020Peer-reviewedCell Biology

iPSC-derived hepatocytes from patients with nonalcoholic fatty liver disease display a disease-specific gene expression profile

C. C. Duwaerts, C. L. Her, N. J. Phillips, H. Willenbring, A. N. Mattis, J. J. Maher

The paper generates iPSC-derived hepatocytes from NAFLD patients to identify disease-specific gene expression profiles without metabolic challenge.

bioRxiv · Apr 20, 2020Pathology

Adipocyte JAK2 mediates aging-associated metabolic liver disease and progression to hepatocellular carcinoma

K. J. Corbit, C. G. Wilson, D. Lowe, J. L. Tran, N. B. Vera, M. Clasquin, A. N. Mattis, E. J. Weiss

This study shows that adipocyte JAK2 mediates GH-induced metabolic liver disease and progression to HCC in aged mice, highlighting adipocytes as key mediators.

bioRxiv · Jun 24, 2019 · PreprintPhysiology