T. TeSlaa

Slow TCA flux implies low ATP production in tumors

This study quantifies TCA flux in tumors and healthy tissues, finding suppressed ATP production in tumors despite increased glycolysis.

Serine catabolism generates NADPH to support hepatic lipogenesis

The paper shows that liver generates NADPH for lipogenesis through serine catabolism, distinct from adipose which uses glucose and the pentose phosphate pathway.