Author

M. D. Blough

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

G. Cairncross· 3 shared J. A. Chan· 2 shared A. Bohm· 1 shared A. D. Rogers· 1 shared A. Gerber· 1 shared C. Binding· 1 shared C. Chen· 1 shared C. Grisdale· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

G. Cairncross

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4 papers

Recent·Most cited

Single-cell landscapes of primary glioblastomas and matched organoids and cell lines reveal variable retention of inter- and intra-tumor heterogeneity

V. G. LeBlanc, D. L. Trinh, S. Aslanpour, M. Hughes, D. Livingstone, M. D. Blough, J. G. Cairncross, J. A. Chan, J. J. Kelly, M. A. Marra

The paper analyzes genetic and transcriptional profiles of glioblastomas, organoids, and cell lines to show variable retention of tumor heterogeneity in organoids and uniformity in cell lines.

bioRxiv · Apr 24, 2021Cancer Biology

Molecular Determinants of Prognosis and Evolution in Diffuse-Lower Grade Astrocytomas

M. Kumar, G. Cairncross, M. D. Blough, P. Bose

This study identifies PDGF pathway activation as a key driver of rapid progression in IDH wild-type low-grade astrocytomas compared to mutant tumors.

bioRxiv · Aug 2, 2020 · PreprintCancer Biology

Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM

A. Bohm, J. DePetro, C. Binding, A. Gerber, N. Chahley, M. Ware, K. Thomas, S. Bukhari, C. Chen, E. Chahley, C. Grisdale, N. D. Berger, S. Lawn, Y. Yu, R. Wong, , G. Cairncross

This study develops a mouse model of glioblastoma (GBM) that replicates its genomic landscape and early stages, enabling research into prevention and treatment strategies.

bioRxiv · Nov 9, 2019 · PreprintCancer Biology

Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

S. T. Ahmad, A. D. Rogers, M. J. Chen, R. Dixit, L. Adnani, L. Frankiw, S. O. Lawn, M. D. Blough, M. Alshehri, W. Wu, S. M. Robbins, G. Cairncross, C. Schuurmans, J. Chan

This study shows that Capicua regulates neural stem cell proliferation and lineage specification by controlling Ets factors, with implications for oligodendroglioma development.

bioRxiv · Feb 13, 2019Cancer Biology