Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids
S. Koster, R. K. Gurumurthy, H. Berger, M. Drabkina, H.-J. Mollenkopf, C. Goosmann, V. Brinkmann, Z. Nagel, M. Mangler, T. F. Meyer, C. Chumduri
This study shows that Chlamydia coinfection with HPV disrupts cellular and genomic integrity safeguards in ectocervical organoids, promoting neoplastic progression.
bioRxiv · Apr 15, 2021 · PreprintCancer Biology