C. Goosmann

Bacterial motility depends on a critical flagellum length and energy-optimised assembly

This study shows that bacterial flagellum assembly is optimized for energy efficiency and motility by balancing secretion rate and filament length.

Identification of a specific granular marker of zebrafish eosinophils enables development of new tools for their study

The paper identifies a specific marker for zebrafish eosinophils and develops new tools to study their biology and function in disease.

FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria

The paper identifies FlhE as a periplasmic chaperone that prevents the formation of periplasmic flagella in Salmonella, which disrupts cell wall synthesis and causes cell lysis.

Generation of a Plasmodium falciparum reporter line for studies of parasite biology throughout the life cycle

This paper generates a new fluorescent reporter parasite strain, PfOBC13GFP, for studying Plasmodium falciparum throughout its life cycle with improved fluorescence and mosquito infectivity.

Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids

This study shows that Chlamydia coinfection with HPV disrupts cellular and genomic integrity safeguards in ectocervical organoids, promoting neoplastic progression.

Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging

The paper uses single-cell genomics and imaging to classify mosquito blood cells, revealing transcriptional signatures and challenges to current morphology-based classification.

Non-competitive resource exploitation within-mosquito shapes evolution of malaria virulence

This study shows that mosquito lipid trafficking affects Plasmodium virulence by shaping sporozoite development and metabolic activity, revealing a vector-driven mechanism in malaria virulence evolution.