Author

H.-J. Mollenkopf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Assay:organoid / primary culture· 2 Assay:proteomics· 2 Approach:wet-lab / biochemical assay· 2

Frequent Co-Authors

H. Berger· 3 shared M. Mangler· 3 shared T. F. Meyer· 3 shared C. Chumduri· 2 shared R. K. Gurumurthy· 2 shared S. Koster· 2 shared V. Brinkmann· 2 shared A. Jacinto· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

H. Berger

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Author profile →

4 papers

Recent·Most cited

Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids

S. Koster, R. K. Gurumurthy, H. Berger, M. Drabkina, H.-J. Mollenkopf, C. Goosmann, V. Brinkmann, Z. Nagel, M. Mangler, T. F. Meyer, C. Chumduri

This study shows that Chlamydia coinfection with HPV disrupts cellular and genomic integrity safeguards in ectocervical organoids, promoting neoplastic progression.

bioRxiv · Apr 15, 2021 · PreprintCancer Biology

Preservation of stemness in high-grade serous ovarian cancer organoids requires low Wnt environment

K. Hoffmann, H. Berger, H. Kulbe, S. Thillainadarasan, H.-J. Mollenkopf, T. Zemojtel, E. Taube, S. Darb-Esfahani, M. Mangler, J. Sehouli, R. Chekerov, E. Braicu, T. F. Meyer, M. Kessler

This study shows that HGSOC organoids require a low Wnt environment for growth, similar to genetically altered FT organoids, indicating early niche changes support tumor outgrowth.

bioRxiv · Aug 21, 2019Cancer Biology

The Aryl Hydrocarbon Receptor senses the Henna pigment Lawsone and mediates Yin-Yang effects on skin homeostasis

L. Lozza, P. Moura-Alves, T. Domaszewska, C. Lage Crespo, I. Streata, A. Kreuchwig, M. Bechtle, M. Klemm, U. Zedler, S. Ungureanu Bogdan, U. Guhlich-Bornhof, A.-B. Koehler, M. Staeber, H.-J. Mollenkopf, R. Hurwitz, , S. H. E. Kaufmann

This study shows that Lawsone, a Henna pigment, activates the AhR receptor in skin cells, with both beneficial and harmful effects depending on the physiological context.

bioRxiv · Nov 4, 2018 · PreprintCell Biology

Transition of Wnt signaling microenvironment delineates the squamo-columnar junction and emergence of squamous metaplasia of the cervix

C. Chumduri, R. K. Gurumurthy, H. Berger, S. Koster, V. Brinkmann, U. Klemm, H.-J. Mollenkopf, H. Herbst, M. Mangler, T. F. Meyer

The paper identifies that Wnt signaling dynamics in the stroma regulate the squamo-columnar junction and the emergence of squamous metaplasia in the cervix, without a localized stem cell population at the boundary.

bioRxiv · Oct 16, 2018Cancer Biology