Author

M. F. van Delft

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. C. S. Huang· 2 shared G. Dewson· 2 shared A. S. Huang· 1 shared B. J. Smith· 1 shared B. Reljic· 1 shared D. A. Stroud· 1 shared F. Sumardy· 1 shared G. Lessene· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

D. C. S. Huang

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2 papers

Recent·Most cited

Molecular definition of the BAK:VDAC2 interaction as a target to manipulate apoptosis

Z. Yuan, M. F. van Delft, M. X. Li, F. Sumardy, B. J. Smith, D. C. S. Huang, G. Lessene, Y. Khakham, R. Jin, S. He, N. A. Smith, R. Birkinshaw, P. E. Czabotar, G. Dewson

This study identifies key residues in the BAK:VDAC2 interaction, showing that disrupting this interaction can inhibit or promote apoptosis depending on the context.

bioRxiv · Dec 13, 2023 · PreprintCell Biology

E3 ubiquitin ligase MARCHF5 controls BAK apoptotic activity independently of BH3-only proteins

G. Dewson, A. S. Huang, H. S. Chin, B. Reljic, T. M. Djajawi, I. K. Tan, D. A. Stroud, D. C. S. Huang, M. F. van Delft

This study identifies MARCHF5 as a regulator of BAK apoptotic activity through ubiquitin ligase activity, independent of BH3-only proteins, and shows its role in drug resistance.

bioRxiv · Jan 4, 2022 · PreprintCell Biology