Author

M. G. Chambers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. A. Pitsillides· 1 shared A. A. Verdegaal· 1 shared A. Chavli· 1 shared B. J. Orlando· 1 shared D. C. Bell· 1 shared F. T. Bekedam· 1 shared G. Birrane· 1 shared G. J. V. M. van Osch· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. A. Pitsillides

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Author profile →

2 papers

Recent·Most cited

In silico, in vitro, and in vivo models reveal EPHA2 as a target for decreasing inflammation and pathological endochondral ossification in osteoarthritis.

M. N. Ferrao Blanco, R. Lesage, N. Kops, N. Fahy, F. T. Bekedam, A. Chavli, Y. M. Bastiaansen-Jenniskens, L. Geris, M. G. Chambers, A. A. Pitsillides, R. Narcisi, G. J. V. M. van Osch

This study identifies EPHA2 as a therapeutic target for osteoarthritis by showing its inhibition reduces inflammation and pathological endochondral ossification in both in vitro and in vivo models.

bioRxiv · Jun 12, 2022Pharmacology & Toxicology

Structure and function of a 9.6 megadalton bacterial iron storage compartment

T. W. Giessen, B. J. Orlando, A. A. Verdegaal, M. G. Chambers, J. Gardener, D. C. Bell, G. Birrane, M. Liao, P. A. Silver

This study characterizes a bacterial iron storage compartment using structural methods, revealing its large iron storage capacity and functional mechanism.

bioRxiv · Jan 3, 2019 · PreprintBiochemistry