Author

N. Fahy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. A. Pitsillides· 1 shared A. Chavli· 1 shared A. Montgomery· 1 shared A.-M. Malfait· 1 shared B. Eckman· 1 shared C. Cuda· 1 shared D. R. Winter· 1 shared F. T. Bekedam· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. A. Pitsillides

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Author profile →

2 papers

Recent·Most cited

In silico, in vitro, and in vivo models reveal EPHA2 as a target for decreasing inflammation and pathological endochondral ossification in osteoarthritis.

M. N. Ferrao Blanco, R. Lesage, N. Kops, N. Fahy, F. T. Bekedam, A. Chavli, Y. M. Bastiaansen-Jenniskens, L. Geris, M. G. Chambers, A. A. Pitsillides, R. Narcisi, G. J. V. M. van Osch

This study identifies EPHA2 as a therapeutic target for osteoarthritis by showing its inhibition reduces inflammation and pathological endochondral ossification in both in vitro and in vivo models.

bioRxiv · Jun 12, 2022Pharmacology & Toxicology

Macrophages drive the inflammatory phase in experimental osteoarthritis

A. Montgomery, N. Fahy, S. Hamilton, B. Eckman, L. De Almeida, S. Ishihara, M. G. Mayr, S.-Y. Chen, G. Gadhvi, C. Cuda, A.-M. Malfait, Y. Bastiaansen-Jenniskens, D. R. Winter

This study shows macrophages drive inflammation in early experimental osteoarthritis by expanding and altering their gene expression in mouse models.

bioRxiv · May 28, 2020 · PreprintImmunology