The influenza A virus endoribonuclease PA-X usurps host mRNA processing machinery to limit host gene expression
L. Gaucherand, B. K. Porter, S. K. Schmaling, C. H. Rycroft, Y. Kevorkian, C. McCormick, D. A. Khaperskyy, M. Gaglia
This study identifies PA-X, an influenza A virus protein, as a factor that selectively targets host mRNAs for degradation by hijacking RNA splicing machinery.
bioRxiv · Oct 14, 2018Microbiology