The CspC pseudoprotease regulates germination of Clostridioides difficile spores in response to multiple environmental signals
A. E. Rohlfing, B. E. Eckenroth, E. R. Forster, Y. Kevorkian, M. L. Donnelly, H. Benito de la Puebla, S. Doublie, A. Shen
This study identifies CspC as a bile salt sensor for C. difficile spore germination and shows it also responds to amino acid and calcium co-germinants through specific residues.
bioRxiv · Nov 5, 2018Microbiology