PIKfyve controls dendritic cell function and tumor immunity
J. E. Choi, Y. Qiao, I. Kryczek, J. Yu, J. Gurkan, Y. Bao, M. Gondal, J. C.-Y. Tien, T. Maj, S. Yazdani, A. Parolia, H. Xia, J. Zhou, S. Wei, S. Grove, , A. M. Chinnaiyan
This study shows that PIKfyve inhibition enhances dendritic cell function and improves immunotherapy efficacy in tumor models.
bioRxiv · Feb 28, 2024Cancer Biology