Author

J. E. Choi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. M. Chinnaiyan· 2 shared Y. Qiao· 2 shared A. Budreika· 1 shared A. Garot· 1 shared A. Parolia· 1 shared B. L. McCollum· 1 shared B. Vuong· 1 shared C. Carrion· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

A. M. Chinnaiyan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PIKfyve controls dendritic cell function and tumor immunity

J. E. Choi, Y. Qiao, I. Kryczek, J. Yu, J. Gurkan, Y. Bao, M. Gondal, J. C.-Y. Tien, T. Maj, S. Yazdani, A. Parolia, H. Xia, J. Zhou, S. Wei, S. Grove, , A. M. Chinnaiyan

This study shows that PIKfyve inhibition enhances dendritic cell function and improves immunotherapy efficacy in tumor models.

bioRxiv · Feb 28, 2024Cancer Biology

Clinically relevant humanized mouse models of metastatic prostate cancer to evaluate cancer therapies

R. J. Kostlan, J. T. Phoenix, A. Budreika, M. G. Ferrari, N. Khurana, J. E. Choi, K. Juckette, B. L. McCollum, R. Moskal, Y. Qiao, D. J. Vander Griend, A. M. Chinnaiyan, S. Kregel

This paper develops humanized mouse models of metastatic prostate cancer to evaluate therapies, showing improved immune interactions and response to hormonal and immunotherapies.

bioRxiv · Oct 13, 2023 · PreprintCancer Biology

The IgH Eμ-MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation

O. Martin, M. Thomas, M. Marquet, A. Garot, M. Brousse, S. Bender, C. Carrion, J. E. Choi, B. Vuong, P. Gearhart, R. Maul, S. Le Noir, E. Pinaud

The paper shows that IgH Eμ-MAR regions limit error-prone repair to the variable region of Ig genes by promoting UNG-dependent repair, affecting somatic hypermutation patterns.

bioRxiv · Aug 15, 2022 · PreprintImmunology

Merkel cell polyomavirus in Merkel cell carcinoma: Integration sites and involvement of the KMT2D tumor suppressor gene

R. Arora, J. E. Choi, P. W. Harms, P. Chandrani

The paper identifies MCV integration sites in Merkel cell carcinoma using whole exome sequencing and finds no highly recurrent sites, with chromosome 5 most frequent and integration enriched near oncogenic transcription factor binding sites.

bioRxiv · Aug 3, 2020Cancer Biology