Author

M. H. Foley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

C. M. Theriot· 4 shared C. M. Pike· 2 shared A. Elmore· 1 shared A. Gulati· 1 shared A. K. Stewart· 1 shared A. M. Rivera· 1 shared A. S. McMillan· 1 shared C. E. Perkins· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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4 shared papersMicrobiology

C. M. Theriot

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multiple TonB Homologs are Important for Carbohydrate Utilization by Bacteroides thetaiotaomicron

R. M. Pollet, M. H. Foley, S. S. Kumar, A. Elmore, N. T. Jabara, S. Venkatesh, G. Vasconcelos Pereira, E. Martens, N. M. Koropatkin

This study identifies TonB4 and TonB6 as functionally redundant in polysaccharide uptake by Bacteroides thetaiotaomicron, with TonB4 being conserved across Bacteroides species.

bioRxiv · Jul 7, 2023 · PreprintMicrobiology

Loss of Bacteroides thetaiotaomicron bile acid altering enzymes impact bacterial fitness and the global metabolic transcriptome

A. S. McMillan, M. H. Foley, C. E. Perkins, C. M. Theriot

This study investigates how Bacteroides thetaiotaomicron's bile acid altering enzymes affect its fitness and metabolic transcriptome under bile acid exposure.

bioRxiv · Jun 27, 2023 · PreprintMicrobiology

The microbial derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota

S. C. Kisthardt, R. Thanissery, C. M. Pike, M. H. Foley, C. M. Theriot

This study shows that bile acid epimers iLCA and iaLCA inhibit C. difficile growth and toxin activity while sparing gut commensals.

bioRxiv · Jun 6, 2023 · PreprintMicrobiology

Distinct bile salt hydrolase substrate preferences dictate C. difficile pathogenesis

M. H. Foley, M. E. Walker, A. K. Stewart, S. O'Flaherty, E. C. Gentry, G. Allen, S. Patel, M. Pan, V. V. Beaty, M. E. Vanhoy, M. K. Dougherty, S. K. McGill, A. Gulati, P. Dorrestein, E. S. Baker, , C. M. Theriot

The paper identifies bile salt hydrolase (BSH) substrate preferences and shows they inhibit C. difficile by altering bile acid pools in CDI models.

bioRxiv · Mar 24, 2022 · PreprintMicrobiology

Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota

J. R. Fletcher, C. M. Pike, R. J. Parsons, A. M. Rivera, M. H. Foley, M. R. McLaren, S. A. Montgomery, C. M. Theriot

This study shows C. difficile uses toxin-induced inflammation to alter host nutrient availability and outcompete Bacteroides by utilizing collagen-derived amino acids.

bioRxiv · Aug 6, 2020Microbiology