Author

S. C. Kisthardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2

Frequent Co-Authors

F. Scholle· 2 shared A. C. Puhl· 1 shared B. L. Hurst· 1 shared B. Yount· 1 shared C. H. Andrade· 1 shared C. M. Pike· 1 shared C. M. Theriot· 1 shared C. Q. Sacramento· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

F. Scholle

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The microbial derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota

S. C. Kisthardt, R. Thanissery, C. M. Pike, M. H. Foley, C. M. Theriot

This study shows that bile acid epimers iLCA and iaLCA inhibit C. difficile growth and toxin activity while sparing gut commensals.

bioRxiv · Jun 6, 2023 · PreprintMicrobiology

Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E

Y. Zhu, F. Scholle, S. C. Kisthardt, D. Xie

This study identifies flavonols and dihydroflavonols as potential inhibitors of SARS-CoV-2 and HCoV-229E main protease activity and viral replication.

bioRxiv · Jul 1, 2021Biochemistry

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

A. C. Puhl, E. J. Fritch, T. R. Lane, L. V. Tse, B. Yount, C. Q. Sacramento, T. A. Tavella, F. T. M. Costa, S. Weston, J. Logue, M. Frieman, L. Premkumar, K. H. Pearce, B. L. Hurst, C. H. Andrade, , S. Ekins

This study evaluates the in vitro antiviral activity of three Ebola and Marburg virus inhibitors against SARS-CoV-2 and explores their potential mechanisms of action.

bioRxiv · Dec 1, 2020Pharmacology & Toxicology