Author

R. Thanissery

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. M. Theriot· 3 shared A. D. Reed· 2 shared A. M. Rivera· 1 shared A. Rivera· 1 shared A. Shen· 1 shared A. Stewart· 1 shared B. J. Callahan· 1 shared C. M. Pike· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMicrobiology

C. M. Theriot

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3 papers

Recent·Most cited

The microbial derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota

S. C. Kisthardt, R. Thanissery, C. M. Pike, M. H. Foley, C. M. Theriot

This study shows that bile acid epimers iLCA and iaLCA inhibit C. difficile growth and toxin activity while sparing gut commensals.

bioRxiv · Jun 6, 2023 · PreprintMicrobiology

The Stickland fermentation precursor trans-4-hydroxyproline differentially impacts the metabolism of Clostridioides difficile and commensal Clostridia

C. M. Theriot, A. D. Reed, J. R. Fletcher, Y. Huang, R. Thanissery, A. M. Rivera, R. J. Parsons, A. Stewart, D. J. Kountz, A. Shen, E. P. Balskus

This study investigates how trans-4-hydroxyproline affects the metabolism of C. difficile and commensal Clostridia, revealing differential gene expression and microbiota changes in mice.

bioRxiv · Nov 12, 2021 · PreprintMicrobiology

Characterization of C. difficile strains isolated from companion animals and the associated changes in the host fecal microbiota

R. Thanissery, M. R. McLaren, A. Rivera, A. D. Reed, N. S. Betrapally, T. Burdette, J. A. Winston, M. Jacob, B. J. Callahan, C. M. Theriot

This study identifies C. difficile strains in companion animals and their impact on host fecal microbiota, showing potential zoonotic transmission and shared ribotypes with human infections.

bioRxiv · Oct 29, 2019 · PreprintMicrobiology