Author

M. H. M. Heemskerk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. A. de Waard· 2 shared M. Griffioen· 2 shared M. L. M. Jongsma· 2 shared R. M. Spaapen· 2 shared S. Bliss· 2 shared T. Verkerk· 2 shared A. H. de Ru· 1 shared A. Mulder· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

A. A. de Waard

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2 papers

Recent·Most cited

ImmunologybioRxivSep 26, 2020

The SPPL3-defined glycosphingolipid repertoire regulates immune responses by improving HLA class I access

M. L. M. Jongsma, M. Raaben, A. A. de Waard…·R. M. Spaapen

The paper identifies a glycosphingolipid (GSL) signature that inhibits HLA-I antigen presentation and shows its reversal by clinically approved drugs.

DOI 10.1016/j.immuni.2020.11.003

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivJun 11, 2020

Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens

A. A. de Waard, T. Verkerk, K. Hoefakker…·R. M. Spaapen

The paper identifies TAP-independent antigen presentation in healthy cells using a T cell clone and highlights the need for comprehensive testing of healthy cell types to safely target antigens for immunotherapy.

DOI 10.1016/j.isci.2021.102051

humanproteomics

𝕏 PostBluesky