Author

M. H. Saier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:E. coli· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Z. Zhang· 3 shared I. A. Rodionova· 2 shared M. Aboulwafa· 2 shared A. Medrano-Soto· 1 shared A. P. McGrath· 1 shared A. V. Sastry· 1 shared B. O. Palsson· 1 shared C.-W. Lee· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersMicrobiology

Z. Zhang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

PtrR (YneJ) is a novel E. coli transcription factor regulating the putrescine stress response and glutamate utilization

I. A. Rodionova, Y. Gao, A. V. Sastry, J. Monk, n. wong, R. Szubin, H. Lim, Z. Zhang, M. H. Saier, B. O. Palsson

This paper identifies PtrR as a dual activator/repressor in E. coli that regulates putrescine stress response and glutamate utilization through transcriptional control of multiple genes.

bioRxiv · Apr 27, 2020 · PreprintMicrobiology

UDP-glucose dehydrogenase Ugd in E. coli is activated by Gmd and RffD, is inhibited by CheY, and regulates swarming

I. A. Rodionova, Z. Zhang, M. Aboulwafa, M. H. Saier

The paper identifies activators and inhibitors of UDP-glucose dehydrogenase Ugd in E. coli and shows its role in swarming behavior.

bioRxiv · Jan 8, 2020 · PreprintBiochemistry

Reclassification of SLC22 Transporters: Analysis of OAT, OCT, OCTN, and other Family Members Reveals 8 Functional Subgroups

D. C. Engelhart, J. Granados, S. K. Nigam, D. Shi, M. H. Saier, M. E. Baker

This paper reclassifies SLC22 transporters into 8 functional subgroups using GWAS, in vivo models, and in vitro assays, revealing shared substrate specificity and subgroup associations.

bioRxiv · Dec 23, 2019Pharmacology & Toxicology

Protein:Protein Interactions in the Cytoplasmic Membrane Influencing Sugar Transport and Phosphorylation Activities of the E. coli Phosphotransferase System.

M. H. Saier, M. Aboulwafa, Z. Zhang

The paper investigates how protein-protein interactions in E. coli's PTS system affect sugar transport and phosphorylation, showing both enhancement and inhibition of different PTS permeases.

bioRxiv · Jun 26, 2019Microbiology

Cryo-EM Structure of OSCA1.2 from Oryza sativa: Mechanical basis of hyperosmolality-gating in Plants

K. Maity, J. Heumann, A. P. McGrath, N. J. Kopcho, P.-K. Hsu, C.-W. Lee, J. H. Mapes, D. Garza, S. Krishnan, G. P. Morgan, A. Medrano-Soto, K. J. Hendargo, T. Klose, S. D. Rees, M. H. Saier, , M. H. B. Stowell

The paper reports the cryo-EM structure of OsOSCA1.2 from rice, revealing its mechanism for sensing hyperosmolality and mediating ion permeability through structural dynamics.

bioRxiv · Dec 30, 2018Biophysics