Author

M. Heck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Cancer Biology· 1 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. K. Erbe· 2 shared J. A. Hank· 2 shared J. Wilson· 2 shared N. Tsarovsky· 2 shared P. M. Sondel· 2 shared A. Bidaud-Meynard· 1 shared A. E. Xu· 1 shared A. Feils· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. K. Erbe

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Bispecific GD2 x B7-H3 Antibody Improves Tumor Targeting and Reduces Toxicity while Maintaining Efficacy for Neuroblastoma

A. K. Erbe, A. S. Feils, A. Hampton, Z. T. Rosenkrans, M. Felder, J. Wiwczar, D. J. Gerhardt, M. Bercher, B. Wenke, C. Haertle, M. Heck, S. N. VandenHeuvel, E. Frankel, M. Nielsen, D. Spiegelman, , P. M. Sondel

bioRxiv · May 23, 2024 · PreprintCancer Biology

Characterization of cotton virus A, a novel and distinct member of the genus Caulimovirus with endogenous viral elements in Gossypium spp.

M. West-Ortiz, D. Stuehler, E. Pollock, J. Wilson, S. Preising, A. Larrea-Sarmiento, O. Alabi, M. Fuchs, M. Heck, A. Olmedo-Velarde

The paper characterizes cotton virus A, a new Caulimovirus, and identifies endogenous viral elements in some cotton species.

bioRxiv · Jun 14, 2023 · PreprintPlant Biology

Antibody landscape of C57BL/6 mice cured of B78 melanoma via immunotherapy

A. Hoefges, S. J. McIlwain, A. K. Erbe, N. N. Mathers, A. E. Xu, D. Melby, K. Tetreault, T. Q. Le, K. Kim, R. S. Pinapati, B. Garcia, J. Patel, M. Heck, A. Feils, N. Tsarovsky, , P. M. Sondel

The paper identifies antibodies targeting melanoma peptides in C57BL/6 mice cured of B78 melanoma via immunotherapy, using proteome arrays and ELISA validation.

bioRxiv · Feb 24, 2023 · PreprintImmunology

Plant production of high affinity nanobodies that block SARS-CoV-2 spike protein binding with its receptor, human angiotensin converting enzyme

M. Pitino, L. A. Fleites, L. Shrum, M. Heck, R. G. Shatters

This study produces nanobodies in plants that block SARS-CoV-2 spike protein binding to ACE2, offering a scalable method for therapeutic development.

bioRxiv · Sep 3, 2022Bioengineering

The innate immunity protein C1QBP functions as a negative regulator of circulative transmission of Potato leafroll virus by aphids

S. L. DeBlasio, J. Wilson, C. Tamborindeguy, R. Johnson, P. V. Pinheiro, M. J. MacCoss, S. M. Gray, M. Heck

This study identifies C1QBP as a negative regulator of Potato leafroll virus transmission by aphids using AP-MS and functional assays.

bioRxiv · Dec 4, 2020Microbiology

The conserved metalloprotease invadolysin is present in invertebrate haemolymph and vertebrate blood

M. Heck, K. Abhinav, L. Feng, E. Morrison, Y. Jung, J. Dear, S. Takahashi

This study identifies invadolysin, a conserved metalloprotease present in invertebrate hemolymph and vertebrate blood, suggesting a role in organismal physiology.

bioRxiv · Apr 17, 2019Cell Biology

A V0-ATPase-dependent apical trafficking pathway maintains the polarity of the intestinal absorptive membrane

A. Bidaud-Meynard, O. Nicolle, M. Heck, G. Michaux

The paper identifies a V0-ATPase-dependent apical trafficking pathway essential for intestinal epithelial polarity and shows its depletion mimics Microvillus inclusion disease defects in C. elegans.

bioRxiv · Dec 10, 2018Cell Biology