Author

M. Helmer-Citterich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

G. Pepe· 3 shared A. Novelletto· 1 shared C. Cirotti· 1 shared C. Contadini· 1 shared D. Barila· 1 shared D. Mougiakakos· 1 shared F. Ballesio· 1 shared F. Frioni· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

G. Pepe

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human lncRNAs harbor conserved modules embedded in different sequence contexts

F. Ballesio, G. Pepe, G. Ausiello, A. Novelletto, M. Helmer-Citterich, P. F. Gherardini

The paper identifies conserved modular exonic regions in human lncRNAs, showing evidence of purifying selection and suggesting functional units similar to protein-coding genes.

bioRxiv · Nov 1, 2023Evolutionary Biology

Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction

S. Latini, V. Venafra, G. Massacci, V. Bica, S. Graziosi, G. M. Pugliese, M. Iannuccelli, F. Frioni, G. Minnella, J. D. Marra, P. Chiusolo, G. Pepe, M. Helmer-Citterich, D. Mougiakakos, M. Boettcher, , F. Sacco

This study develops a systems-based strategy to predict drug sensitivity in FLT3-ITD AML by integrating genomic, transcriptomic data with a prior-knowledge signaling network.

bioRxiv · Jun 22, 2023Cancer Biology

NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma

D. Barila, C. Cirotti, I. Taddei, C. Contadini, G. Pepe, M. De Bardi, G. Borsellino, M. Helmer-Citterich

This study identifies a molecular link between Src tyrosine kinase and ferroptosis resistance in glioblastoma through NRF2 pathway activation, suggesting a potential therapeutic target.

bioRxiv · May 8, 2023Cancer Biology