M. Hoelscher

This study shows that prior TBEV immunity alters the YF17D vaccine response, leading to cross-reactive antibodies that increase the risk of ADE for dengue and Zika.

SARS-CoV-2 Beta variant infection generates lineage-specific antibodies and cross-reactive antibodies with neutralizing activity against wild-type and other variants.

This study identifies acriflavine as a potent inhibitor of SARS-CoV-2 and other betacoronaviruses, effective in cellular models, in vivo, and ex vivo.

This study identifies an early interferon-stimulated gene (ISG) upregulation as a protective immune signature in non-pneumonic SARS-CoV-2 infection, preventing progression to pneumonia.

PET imaging of CCR2+ cells in lung fibrosis identifies therapeutic response in mouse models and shows perifibrotic signal in IPF patients.

This study evaluates the Molecular Bacterial Load assay (MBLA) for diagnosing and monitoring tuberculosis treatment response, finding it provides reliable, contamination-resistant results faster than traditional methods.