The translational landscape of SARS-CoV-2 and infected cells
M. Puray-Chavez, K. Tenneti, N. Lee, Y. Wang, H. R. Vuong, Y. Liu, A. Horani, T. Huang, S. P. Gunsten, J. B. Case, W. Yang, M. S. Diamond, S. L. Brody, J. Dougherty, S. B. Kutluay
This study uses ribosome profiling to analyze SARS-CoV-2 and host mRNA translation in infected cells, finding that viral mRNAs are not more efficiently translated than host mRNAs and highlighting unique translational strategies.
bioRxiv · Nov 3, 2020 · PreprintMicrobiology