Author

A. M. Bergman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

W. Zwart· 5 shared F. Y. Feng· 2 shared H. van der Poel· 2 shared S. Linder· 2 shared A. A. Hamid· 1 shared A. G. Sowalsky· 1 shared A. T. Ku· 1 shared A. Zaalberg· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersCancer Biology

W. Zwart

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

A. Zaalberg, E. Minnee, I. Mayayo-Peralta, K. Schuurman, S. Gregoricchio, T. A. van Schaik, L. Hoekman, D. Li, E. Corey, H. Janssen, C. Lieftink, S. Prekovic, M. Altelaar, P. S. Nelson, R. Beijersbergen, , A. M. Bergman

This study uses a CRISPR screen to identify genes critical for macrophage-mediated killing of prostate cancer cells, revealing AR as an immunomodulator that promotes resistance to macrophage attack.

bioRxiv · Jun 6, 2023Cancer Biology

Loss of tristetraprolin activates NF-κB induced phenotypic plasticity and primes transition to lethal prostate cancer

K. L. Morel, A. A. Hamid, B. G. Falcon, J. N. Singh, S. Linder, A. M. Bergman, H. G. van der Poel, I. Hofland, E. M. Bekers, S. Trostel, S. Wilkinson, A. T. Ku, D. L. Burkhart, M. Kim, J. Kim, , L. Ellis

This study shows that loss of ZFP36 promotes NF-κB activation and phenotypic plasticity in prostate cancer, leading to aggressive disease and castration resistance, which can be reversed by NF-κB inhibition.

bioRxiv · Aug 5, 2022 · PreprintCancer Biology

Functional mapping of androgen receptor enhancer activity

C.-C. F. Huang, S. Lingadahalli, T. Morova, D. Ozturan, E. Hu, I. P. L. Yu, S. Linder, M. Hoogstraat, S. Stelloo, F. Sar, H. van der Poel, U. B. Altintas, M. Saffarzadeh, S. Le Bihan, B. McConeghy, , N. A. Lack

The paper functionally maps AR enhancer activity using STARRseq, finding most AR binding sites are inactive or constitutively active, with inducible enhancers forming regulatory hubs that drive gene transcription.

bioRxiv · Aug 18, 2020Cancer Biology

Human Prostate Cancer-Associated Macrophage Subtypes with Prognostic Potential Revealed by Single-cell Transcriptomics

J. C. Siefert, B. Cioni, M. J. Muraro, M. Alshalalfa, J. Vivie, H. van der Poel, F. Y. Feng, L. Wessels, W. Zwart, A. M. Bergman

The paper identifies three macrophage subtypes in human prostate cancer using single-cell transcriptomics and develops a gene signature linked to patient survival.

bioRxiv · Jun 19, 2020Immunology

The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

L. F. van Dessel, J. van Riet, M. Smits, Y. Zhu, P. Hamberg, M. S. van der Heijden, A. M. Bergman, I. M. van Oort, R. de Wit, E. E. Voest, N. Steeghs, T. N. Yamaguchi, J. Livingstone, P. C. Boutros, J. W. M. Martens, , M. P. Lolkema

This study uses whole-genome sequencing to identify four distinct genotypes in metastatic castration-resistant prostate cancers, with potential clinical implications for patient stratification.

bioRxiv · Oct 7, 2019Cancer Biology