Author

K. Schuurman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

W. Zwart· 3 shared C. Lieftink· 2 shared L. Hoekman· 2 shared M. Altelaar· 2 shared R. Beijersbergen· 2 shared S. Gregoricchio· 2 shared S. Prekovic· 2 shared A. A. Singh· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

W. Zwart

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Author profile →

3 papers

Recent·Most cited

Enhancer plasticity in endometrial tumorigenesis demarcates non-coding somatic mutations and 3D-genome alterations boosting the oncogenic driver ESR1

S. Gregoricchio, A. Kojic, M. Hoogstraat, K. Schuurman, S. Stelloo, T. M. Severson, T. A. O'Mara, M. Droog, A. A. Singh, D. M. Glubb, L. F. A. Wessels, M. Vermeulen, F. van Leeuwen, W. Zwart

The paper identifies enhancer plasticity and 3D-genome alterations in endometrial cancer that boost ESR1 expression through non-coding mutations and risk variants.

bioRxiv · Jul 25, 2023Cancer Biology

A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

A. Zaalberg, E. Minnee, I. Mayayo-Peralta, K. Schuurman, S. Gregoricchio, T. A. van Schaik, L. Hoekman, D. Li, E. Corey, H. Janssen, C. Lieftink, S. Prekovic, M. Altelaar, P. S. Nelson, R. Beijersbergen, , A. M. Bergman

This study uses a CRISPR screen to identify genes critical for macrophage-mediated killing of prostate cancer cells, revealing AR as an immunomodulator that promotes resistance to macrophage attack.

bioRxiv · Jun 6, 2023Cancer Biology

Glucocorticoids regulate cancer cell dormancy

S. Prekovic, K. Schuurman, A. Gonzalez Manjon, M. Buijs, I. Mayayo Peralta, M. D. Wellenstein, S. Yavuz, A. Barrera, K. Monkhorst, A. Huber, B. Morris, C. Lieftink, J. Silva, B. Györffy, L. Hoekman, , W. Zwart

This study identifies the mechanism by which glucocorticoid receptor activation induces cancer cell dormancy through CDKN1C and FOXO1/IRS2 signaling, with implications for cancer therapy.

bioRxiv · Sep 4, 2019 · PreprintCancer Biology