Author

M. I. Parker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

R. L. Dunbrack· 2 shared A. Mihai· 1 shared A. V. Contreras· 1 shared B. Faezov· 1 shared B. Zhang· 1 shared C. W. Murray· 1 shared D. L. Wiest· 1 shared D. Petrov· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

R. L. Dunbrack

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Author profile →

3 papers

Recent·Most cited

E protein control of NKgammadeltaT cell development through both generation and function of the stereotypic Vgamma1Vdelta6.3 TCR

D. L. Wiest, A. Mihai, S.-Y. Lee, S. Shinton, M. I. Parker, A. V. Contreras, B. Zhang, M. Rhodes, R. L. Dunbrack, J. C. Zuniga-Pflucker, M. Ciofani, Y. Zhuang

This study shows that Id3 deficiency affects the development of gamma delta T cell subsets by regulating the generation and function of the Vgamma1Vdelta6.3 TCR.

bioRxiv · Jan 4, 2024 · PreprintImmunology

A penultimate classification of canonical antibody CDR conformations

S. Kelow, B. Faezov, Q. Xu, M. I. Parker, J. Adolf-Bryfogle, R. L. Dunbrack

The paper updates the classification of antibody CDR conformations using improved clustering methods and electron density validation, identifying new clusters and retiring outdated ones.

bioRxiv · Oct 12, 2022 · PreprintImmunology

Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth

R. Tang, E. G. Shuldiner, M. Kelly, C. W. Murray, J. D. Hebert, L. Andrejka, M. K. Tsai, N. W. Hughes, M. I. Parker, H. Cai, Y.-C. Li, G. Wahl, R. Dunbrack, P. K. Jackson, D. Petrov, M. M. Winslow

This study identifies HRAS and NRAS as suppressors of KRASG12D-driven lung cancer using CRISPR screens in mouse models and confirms their role in human cell lines.

bioRxiv · Jul 8, 2021 · PreprintCancer Biology