Author

M. Iino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

J. Suzuki· 2 shared K. Kanemaru· 2 shared N. Kurebayashi· 2 shared T. Murayama· 2 shared T. Sakurai· 2 shared A. Miura· 1 shared F. Yamashita· 1 shared H. Kagechika· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. Suzuki

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2 papers

Recent·Most cited

Screening for novel RyR2 inhibitors by ER Ca2+ monitoring

M. Takenaka, M. Kodama, T. Murayama, M. Ishigami-Yuasa, S. Mori, R. Ishida, J. Suzuki, K. Kanemaru, M. Sugihara, M. Iino, A. Miura, H. Nishio, S. Morimoto, H. Kagechika, T. Sakurai, N. Kurebayashi

This study identifies three RyR2 inhibitors using an ER Ca2+ monitoring assay, showing they suppress arrhythmogenic Ca2+ waves without affecting normal Ca2+ transients.

bioRxiv · Aug 21, 2023 · PreprintPharmacology & Toxicology

Enhanced CICR activity reduces ER Ca2+ level in cells expressing CPVT-linked mutant RyR2

N. Kurebayashi, T. Murayama, R. Ohta, J. Suzuki, K. Kanemaru, S. Ohno, M. Horie, M. Iino, F. Yamashita, T. Sakurai

This paper quantitatively examines how CPVT-linked RyR2 mutations affect ER Ca2+ release threshold by measuring CICR activity and simulating cellular responses.

bioRxiv · Jan 16, 2021Physiology