M. J. Ryan

Horizontal transfers between fungal Fusarium species contributed to successive outbreaks of coffee wilt disease

This study identifies horizontal gene transfers from Fusarium oxysporum to Fusarium xylarioides as a mechanism driving the repeated outbreaks of coffee wilt disease.

Water inside the selectivity filter of a K+ ion channel: structural heterogeneity, picosecond dynamics, and hydrogen-bonding

This study uses 2D IR spectroscopy and simulations to analyze water dynamics and K+ ion behavior in the KcsA channel selectivity filter, revealing structural heterogeneity and distinct reorientation timescales.

Spatial learning overshadows learning novel odors and sounds in both a predatory and a frugivorous bat

This study compares spatial and feature cue learning in predatory and frugivorous bats, finding both species prioritize spatial cues over odors or sounds.

Long-term memory in frog-eating bats

The study tests long-term memory retention in wild-caught frog-eating bats by re-capturing them after 1-4 years and re-testing their response to novel acoustic cues.

Modulation of ferroptosis sensitivity by TXNRD1 in pancreatic cancer cells

This study shows that reducing TXNRD1 in pancreatic cancer cells increases resistance to ferroptosis by boosting GPX4 levels, highlighting context-specific ferroptosis regulation.

Floating frogs sound larger: environmental constraints on signal production drives call frequency changes

The paper investigates how altering the environment of calling frogs affects their vocalization frequency by manipulating water levels and observing changes in air pressure and airflow.

Targeting a Therapy-Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors

This paper identifies nitrile oxide electrophiles as a new class of GPX4 inhibitors that overcome limitations of existing chloroacetamide-based inhibitors.