Author

M. J. van Hemert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. Thaler· 4 shared E. J. Snijder· 3 shared A. Tas· 2 shared C. Salgado-Benvindo· 2 shared D. Ninaber· 2 shared P. Hiemstra· 2 shared P. J. Bredenbeek· 2 shared Y. Wang· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersMicrobiology

M. Thaler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells

C. R. Pothast, R. C. Dijkland, M. Thaler, R. S. Hagedoorn, M. G. Kester, A. K. Wouters, P. S. Hiemstra, M. J. van Hemert, S. Gras, J. F. Falkenburg, M. H. Heemskerk

The paper shows that CMV-specific T cells can cross-react with SARS-CoV-2, contributing to pre-existing immunity despite low sequence homology.

bioRxiv · Jul 31, 2022Immunology

Honokiol inhibits SARS-CoV-2 replication in cell culture

C. Salgado-Benvindo, A. A. Leijs, M. Thaler, A. Tas, J. L. Arbiser, E. J. Snijder, M. J. van Hemert

This study shows honokiol inhibits SARS-CoV-2 replication in cell culture with EC50 of 7.8 μM, effective against variants like Omicron and other human coronaviruses.

bioRxiv · Jul 26, 2022 · PreprintMicrobiology

Impact of human airway epithelial cellular composition on SARS-CoV-2 infection biology

Y. Wang, M. Thaler, D. Ninaber, A. M. van der Does, N. S. S. Ogando, H. Beckert, C. Taube, C. Salgado Benvindo Da Silva, E. J. Snijder, P. J. Bredenbeek, P. Hiemstra, M. J. van Hemert

This study examines how the composition of human airway epithelial cells affects SARS-CoV-2 infection, finding that prolonged culture time and higher proportions of ciliated and goblet cells increase viral load.

bioRxiv · Jul 21, 2021 · PreprintCell Biology

Suramin inhibits SARS-CoV-2 infection in cell culture by interfering with early steps of the replication cycle

C. Salgado-Benvindo, M. Thaler, A. Tas, N. S. Ogando, P. J. Bredenbeek, D. Ninaber, Y. Wang, P. Hiemstra, E. J. Snijder, M. J. van Hemert

This study shows suramin inhibits SARS-CoV-2 replication in cell cultures by targeting early replication steps, with potential for clinical evaluation.

bioRxiv · May 6, 2020Microbiology