Author

N. S. Ogando

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

E. J. Snijder· 2 shared A. Tas· 1 shared C. C. Posthuma· 1 shared C. Salgado-Benvindo· 1 shared D. Ninaber· 1 shared J. Zevenhoven-Dobbe· 1 shared M. J. van Hemert· 1 shared M. Thaler· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

E. J. Snijder

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2 papers

Recent·Most cited

The enzymatic activity of the nsp14 exoribonuclease is critical for replication of Middle East respiratory syndrome-coronavirus

N. S. Ogando, J. Zevenhoven-Dobbe, C. C. Posthuma, E. J. Snijder

This study shows that the ExoN activity of MERS-CoV nsp14 is essential for viral RNA synthesis, unlike in MHV and SARS-CoV where it primarily enhances replication fidelity.

Journal of Virology · Nov 9, 2020Peer-reviewedMicrobiology

Suramin inhibits SARS-CoV-2 infection in cell culture by interfering with early steps of the replication cycle

C. Salgado-Benvindo, M. Thaler, A. Tas, N. S. Ogando, P. J. Bredenbeek, D. Ninaber, Y. Wang, P. Hiemstra, E. J. Snijder, M. J. van Hemert

This study shows suramin inhibits SARS-CoV-2 replication in cell cultures by targeting early replication steps, with potential for clinical evaluation.

bioRxiv · May 6, 2020Microbiology