Author

M. Joppe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 2 Organism:yeast· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

M. Grininger· 3 shared E. D'Imprima· 2 shared A. Rittner· 1 shared D. Floris· 1 shared D. H. Sherman· 1 shared E. Heid· 1 shared J. J. Schmidt· 1 shared J. Vonck· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBiochemistry

M. Grininger

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Author profile →

3 papers

Recent·Most cited

Directed biosynthesis of fluorinated polyketides

A. Rittner, M. Joppe, J. J. Schmidt, L. M. Mayer, E. Heid, D. H. Sherman, M. Grininger

This paper describes a method to directly fluorinate polyketides using a modified PKS enzyme, demonstrating its application in creating a fluorinated antibiotic derivative.

bioRxiv · Jul 30, 2021 · PreprintBiochemistry

The resolution revolution in cryoEM requires new sample preparation procedures: A rapid pipeline to high resolution maps of yeast FAS

M. Joppe, E. D'Imprima, N. Salustros, K. S. Paithankar, J. Vonck, M. Grininger, W. Kuehlbrandt

The paper introduces a rapid pipeline for producing high-resolution cryoEM maps of yeast FAS, achieving a 3.1 Å map from 15,000 particles in one day.

bioRxiv · Nov 4, 2019Biochemistry

The deadly touch: protein denaturation at the water-air interface and how to prevent it

E. D'Imprima, D. Floris, M. Joppe, R. Sanchez, M. Grininger, W. Kühlbrandt

The paper investigates protein denaturation at the air-water interface using electron cryo-microscopy and shows that hydrophilized graphene prevents this denaturation.

bioRxiv · Aug 25, 2018Biophysics