Author

T. Boettler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Bengsch· 2 shared C. Neumann-Haefelin· 2 shared M. Hofmann· 2 shared M. Panning· 2 shared R. Thimme· 2 shared V. L. Dao Thi· 2 shared A. Decker· 1 shared A. Nieters· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

B. Bengsch

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A high-content RNA-based imaging assay reveals integrin beta 1 as a cofactor for cell entry of non-enveloped hepatitis E virus

R. M. Fu, Z. Engels, J. A. Wheis, J. Muerle, M. Kloehn, D. Todt, J. Hu, E. Steinmann, T. Boettler, P.-Y. Lozach, S. M. Lemon, V. L. Dao Thi

This study identifies integrin beta 1 as a cofactor for naked hepatitis E virus entry, revealing distinct endocytic pathways for naked and enveloped HEV particles.

bioRxiv · Oct 27, 2023 · PreprintMicrobiology

Efficient formation and maintenance of humoral and CD4 T cell immunity targeting the viral capsid in acute-resolving hepatitis E infection

B. Csernalabics, M. S. Marinescu, L. Maurer, L. Kelsch, J. Werner, K. Baumann, K. Zoldan, M. Panning, P. Reuken, T. Bruns, B. Bengsch, C. Neumann-Haefelin, M. Hofmann, R. Thimme, V. L. Dao Thi, T. Boettler

The paper longitudinally characterizes HEV-specific CD4 T cells and neutralizing antibodies targeting nHEV and eHEV in acute and resolved HEV infection, finding capsid-specific immunity dominates and correlates with nAb responses.

bioRxiv · Oct 19, 2023Immunology

Ex vivo detection of SARS-CoV-2-specific CD8+ T cells: rapid induction, prolonged contraction, and formation of functional memory

I. Schulien, J. Kemming, V. Oberhardt, K. Wild, L. M. Seidel, S. Killmer, Sagar, F. Daul, M. Salvat Lago, A. Decker, H. Luxenburger, B. Binder, D. Bettinger, O. Sogukpinar, S. Rieg, , C. Neumann-Haefelin

This study identifies SARS-CoV-2-specific CD8+ T-cell responses, showing their rapid induction, prolonged contraction, and functional memory formation compared to antibody responses.

bioRxiv · Aug 13, 2020 · PreprintImmunology