M. Kolbe

Novel Multi-Epitope Vaccine candidate derived from critically important proteins of Monkeypox isolates

This paper identifies and designs multi-epitope vaccine candidates from monkeypox virus proteins using in silico methods, finding highly conserved and immunogenic epitopes suitable for vaccine development.

Novel 'GaEl antigenic patches' identified by 'reverse epitomics' approach to design multi-patch vaccines against NIPAH infection, a silent threat to global human health

This paper identifies novel antigenic patches using reverse epitomics to design multi-patch vaccines against Nipah virus, showing broad population coverage and stable molecular interactions.

Exploring the structural basis to develop efficient multi-epitope vaccines displaying interaction with HLA and TAP and TLR3 molecules to prevent NIPAH infection, a global threat to human health

This paper designs and in silico validates two multi-epitope vaccines against Nipah virus, incorporating CTL and HTL epitopes, B cell epitopes, and adjuvants, with potential for effective and specific immune response.

Novel method for quantifying AhR-ligand binding affinities using Microscale Thermophoresis

This paper introduces a new microscale thermophoresis method to quantify AhR-ligand binding affinities and identify potential selective AhR modulators.

Computationally validated SARS-CoV-2 CTL and HTL Multi-Patch Vaccines designed by reverse epitomics approach, shows potential to cover large ethnically distributed human population worldwide

This paper designs and validates Multi-Patch Vaccines against SARS-CoV-2 using a reverse epitomics approach, showing potential to cover a large ethnically diverse human population.

Flagella methylation promotes bacterial adhesion and host cell invasion

This study shows that flagellin methylation in Salmonella enhances adhesion and invasion by increasing surface hydrophobicity, aiding gut colonization and host infection.

Molecular organization of soluble type III secretion system sorting platform complexes

The paper reconstitutes and characterizes the molecular structure of the Salmonella Typhimurium T3SS sorting platform, revealing its stoichiometry and L-shaped conformation.