Author

S. H. E. Kaufmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Stinn· 1 shared C. R. de Almeida· 1 shared G. Krishnamoorthy· 1 shared J. Furkert· 1 shared J. Weiner· 1 shared M. Fontes· 1 shared M. Kolbe· 1 shared M. Martinez-Lopez· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. Stinn

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Macrophages drive the earliest anti-tumoral response to BCG therapy by directly killing bladder cancer through TNF signaling

M. Martinez-Lopez, C. R. de Almeida, M. Fontes, R. V. Mendes, S. H. E. Kaufmann, R. Fior

This study identifies macrophages as key drivers of BCG therapy's anti-tumoral effect through direct TNF-mediated cancer cell killing, independent of adaptive immunity.

bioRxiv · Jan 5, 2024 · PreprintCancer Biology

Novel method for quantifying AhR-ligand binding affinities using Microscale Thermophoresis

P. Moura Alves, S. H. E. Kaufmann, A. Stinn, M. Kolbe, J. Furkert

This paper introduces a new microscale thermophoresis method to quantify AhR-ligand binding affinities and identify potential selective AhR modulators.

Biosensors · Feb 24, 2021Peer-reviewedBiochemistry

Inhibition of host Lactate dehydrogenase A by a small-molecule limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid

G. Krishnamoorthy, P. Kaiser, U. Abu Abed, J. Weiner, P. Moura-Alves, V. Brinkmann, S. H. E. Kaufmann

This paper shows that inhibiting host LDHA with FX11 limits M. tuberculosis growth and enhances the effectiveness of isoniazid in a mouse model of TB.

bioRxiv · May 7, 2019 · PreprintMicrobiology