Author

A. K. Saxena

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 2 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

M. Kamthania· 2 shared M. Kolbe· 2 shared S. Srivastava· 2 shared S. Verma· 2 shared A. Bandyopadyay· 1 shared A. Bansal· 1 shared A. K. Gupta· 1 shared A. K. Srivastava· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

M. Kamthania

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Author profile →

6 papers

Recent·Most cited

Dissection of function and recognition mechanism of M. tuberculosis ESX-1 secreted virulence factor EspC

R. Sharma, V. K. Kashyap, M. Kumar, A. Bansal, A. K. Saxena

The paper investigates the function and recognition mechanism of M. tuberculosis ESX-1 virulence factor EspC and its interaction with EccA1 ATPase, identifying key binding regions and their impact on secretion.

bioRxiv · Sep 24, 2021 · PreprintBiophysics

Exploring the structural basis to develop efficient multi-epitope vaccines displaying interaction with HLA and TAP and TLR3 molecules to prevent NIPAH infection, a global threat to human health

S. Srivastava, S. Verma, M. Kamthania, A. K. Saxena, K. Pandey, M. Kolbe

This paper designs and in silico validates two multi-epitope vaccines against Nipah virus, incorporating CTL and HTL epitopes, B cell epitopes, and adjuvants, with potential for effective and specific immune response.

bioRxiv · Sep 17, 2021 · PreprintImmunology

Structural and biochemical analysis of ATPase activity and EsxAB substrate binding of M. tuberculosis EccCb1 enzyme

A. Bandyopadyay, A. K. Saxena

This study analyzes the ATPase activity and EsxAB substrate binding of M. tuberculosis EccCb1 enzyme using structural and biochemical methods, revealing its mechanism and potential for antivirulence drug development.

bioRxiv · May 31, 2021 · PreprintBiophysics

Computationally validated SARS-CoV-2 CTL and HTL Multi-Patch Vaccines designed by reverse epitomics approach, shows potential to cover large ethnically distributed human population worldwide

S. Srivastava, S. Verma, M. Kamthania, D. Agarwal, A. K. Saxena, M. Kolbe, S. Singh, A. Kotnis, B. Rathi, S. A. Nayar, H.-J. Shin, K. Vashisht, K. C. Pandey

This paper designs and validates Multi-Patch Vaccines against SARS-CoV-2 using a reverse epitomics approach, showing potential to cover a large ethnically diverse human population.

bioRxiv · Sep 6, 2020Immunology

Synthesis, SAR and Docking Studies of Substituted Aryl phenylthiazolyl phenylcarboxamide as potential PTP-1B Inhibitors

K. Varshney, A. K. Gupta, A. Rawat, R. Srivastava, A. Mishra, M. Saxena, A. K. Srivastava, S. Jain, A. K. Saxena

The paper synthesizes and evaluates substituted aryl phenylthiazolyl phenylcarboxamides as PTP-1B inhibitors, identifying compound 38 as a potent inhibitor with in vivo metabolic benefits.

bioRxiv · Mar 4, 2019Pharmacology & Toxicology

The impact of distillery effluent irrigation on plant-growth-promoting traits and taxonomic composition of bacterial communities in agricultural soil

P. Kumari, B. M. Tripathi, R. N. Singh, A. K. Saxena, R. Kaushik

This study examines how distillery effluent irrigation affects bacterial PGP traits and taxonomic composition in agricultural soil, finding no severe impact on these factors.

bioRxiv · Feb 19, 2019 · PreprintMicrobiology