Author

M. Lifton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:flow cytometry· 1 Organism:human· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

A. Chandrashekar· 2 shared A. Cook· 2 shared A. J. Martinot· 2 shared A. Van Ry· 2 shared D. H. Barouch· 2 shared E. Teow· 2 shared H. Andersen· 2 shared J. Liu· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Chandrashekar

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Upregulation of the NKG2D ligand ULBP2 by JC polyomavirus infection promotes immune recognition by natural killer cells.

S. Jost, J. Ahn, S. Chen, T. Yoder, K. E. Gikundiro, E. Lee, S. B. Gressens, K. Kroll, M. Craemer, G. C. Kaynor, M. Lifton, C. S. Tan

This study shows that NK cells can eliminate JCPyV-infected cells through NKG2D-ULBP2 interaction, suggesting this pathway as a potential immunotherapeutic target for PML.

The Journal of Infectious Diseases · Sep 29, 2023Peer-reviewedImmunology

Vaccine Protection Against the SARS-CoV-2 Omicron Variant in Macaques

A. Chandrashekar, J. Yu, K. McMahan, C. Jacob-Dolan, J. Liu, X. He, D. Hope, T. Anioke, J. Barrett, B. Chung, N. Hachmann, M. Lifton, J. Miller, O. Powers, M. Sciacca, , D. H. Barouch

This study evaluates vaccine efficacy against SARS-CoV-2 Omicron in macaques, finding that both humoral and cellular immune responses are necessary for virologic control.

bioRxiv · Feb 6, 2022Microbiology

Low-Dose Ad26.COV2.S Protection Against SARS-CoV-2 Challenge in Rhesus Macaques

X. He, A. Chandrashekar, R. C. Zahn, F. Wegmann, J. Yu, N. B. Mercado, K. McMahan, A. J. Martinot, C. Piedra-Mora, S. Beecy, S. Ducat, R. Chamanza, S. Rosendahl Huber, L. van der Fits, E. N. Borducchi, , D. H. Barouch

This study shows that low doses of Ad26.COV2.S vaccine protect rhesus macaques against SARS-CoV-2 challenge, with higher doses needed for upper respiratory tract protection.

bioRxiv · Jan 27, 2021Immunology