BiochemistrybioRxiv
Kinome screening identifies integrated stress response kinase EIF2AK1 / HRI as a negative regulator of PINK1 mitophagy signaling
P. Singh, S. Agarwal, I. Volpi…·M. M. K. Muqit
The paper identifies EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signaling through siRNA screening and pharmacological inhibition.
DOI 10.1126/sciadv.adn2528