Author

M. Mahalingam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

V. B. Rao· 3 shared H. Batra· 2 shared S. Jain· 2 shared C. Beck· 1 shared C. Lange· 1 shared C. Zhong· 1 shared D. Kihara· 1 shared D. Singh· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

V. B. Rao

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeted Bacteriophage T4 Nanoparticles Reverse HIV-1 Latency in CD4+ Human T Cells

H. Batra, J. Zhu, S. Jain, N. Ananthaswamy, M. Mahalingam, P. Tao, C. Lange, S. Hill, C. Zhong, M. F. Kearney, H. Hu, F. Maldarelli, V. B. Rao

The paper shows that CD4-targeted bacteriophage T4 nanoparticles reactivate HIV-1 latency in CD4+ T-cells without global activation or cytokine storm.

bioRxiv · Jul 20, 2021 · PreprintImmunology

A Remarkable Genetic Shift in a Transmitted/Founder Virus Broadens Antibody Responses Against HIV-1

S. Jain, G. Uritskiy, M. Mahalingam, H. Batra, S. Chand, H. Trinh, C. Beck, W.-H. Shin, W. AlSalmi, G. Kijak, L. A. Eller, J. Kim, D. Kihara, S. Tovanabutra, G. Ferrari, , V. B. Rao

The paper identifies a genetic shift in an HIV-1 transmitted/founder virus that leads to broader antibody responses by altering the V2 domain structure.

bioRxiv · Jun 16, 2021Microbiology

A viral genome packaging ring-ATPase is a flexibly coordinated pentamer

L. Dai, D. Singh, S. Lu, V. Kottadiel, R. Vafabakhsh, M. Mahalingam, Y. R. Chemla, T. Ha, V. B. Rao

The paper determines the composition of the bacteriophage T4 DNA packaging motor and shows that it can tolerate an inactive subunit, challenging the idea of strict coordination among motor subunits.

bioRxiv · Mar 8, 2021Biophysics