Author

C. Lange

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Kalsdorf· 2 shared S. Niemann· 2 shared A. Gillis· 1 shared A. Gross· 1 shared A. Hoelscher· 1 shared A. Kispert· 1 shared A. Laudisoit· 1 shared A. Ondzie· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

B. Kalsdorf

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Serratia sp. dominates the lung microbiome of patients with tuberculosis and non-tuberculous mycobacterial lung diseases

M. Belheouane, B. Kalsdorf, S. Niemann, K. I. Gaede, C. Lange, J. Heyckendorf, M. Merker

This study identifies Serratia sp. as a dominant genus in the lung microbiome of TB and NTM-LD patients, with specific ASVs associated with disease states.

bioRxiv · May 27, 2024 · PreprintMicrobiology

Targeted Bacteriophage T4 Nanoparticles Reverse HIV-1 Latency in CD4+ Human T Cells

H. Batra, J. Zhu, S. Jain, N. Ananthaswamy, M. Mahalingam, P. Tao, C. Lange, S. Hill, C. Zhong, M. F. Kearney, H. Hu, F. Maldarelli, V. B. Rao

The paper shows that CD4-targeted bacteriophage T4 nanoparticles reactivate HIV-1 latency in CD4+ T-cells without global activation or cytokine storm.

bioRxiv · Jul 20, 2021 · PreprintImmunology

Coronavirus surveillance in Congo basin wildlife detects RNA of multiple species circulating in bats and rodents

C. Kumakamba, F. R. Niama, F. Muyembe, J.-V. Mombouli, P. M. Kingebeni, R. A. Nina, I. N. Lukusa, G. Bounga, F. NKawa, C. G. Nkoua, J. Atibu Losoma, P. Mulembakani, M. Makuwa, U. Tamufe, A. Gillis, , C. Lange

The paper surveys coronaviruses in Congo Basin wildlife, finding RNA in 121 animals, mostly bats, with some sequences closely related to human coronaviruses.

bioRxiv · Jul 20, 2020Microbiology

WNT6-ACC2-induced accumulation of triacylglycerol rich lipid droplets is exploited by Mycobacterium tuberculosis

J. Brandenburg, S. Marwitz, S. C. Tazoll, F. Waldow, B. Kalsdorf, T. Vierbuchen, T. Scholzen, A. Gross, S. Goldenbaum, A. Hoelscher, M. Hein, L. Linnemann, M. Reimann, A. Kispert, M. Leitges, , N. Reiling

This study shows that the WNT6-ACC2 pathway promotes lipid droplet accumulation in macrophages, which Mycobacterium tuberculosis exploits for growth, and that inhibiting this pathway enhances anti-tuberculosis treatment.

bioRxiv · Jun 26, 2020 · PreprintImmunology