Author

L. Perez Vidakovics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Organism:rat· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. Murrell· 4 shared J. M. Coquet· 4 shared L. Hanke· 4 shared A. Pankow· 3 shared C. Kim· 3 shared D. J. Sheward· 3 shared E. Urgard· 3 shared G. M. McInerney· 3 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

B. Murrell

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Author profile →

4 papers

Recent·Most cited

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralising SARS-CoV-2 nanobodies

L. Hanke, D. J. Sheward, A. Pankow, L. Perez Vidakovics, V. Karl, C. Kim, E. Urgard, N. L. Smith, J. Astorga-Wells, S. Ekström, J. M. Coquet, G. M. McInerney, B. Murrell

This study identifies potent cross-neutralizing SARS-CoV-2 nanobodies from an alpaca immune repertoire using phage display and epitope mapping.

bioRxiv · Jul 25, 2021Immunology

Driving potent neutralization of a SARS-CoV-2 Variant of Concern with a heterotypic boost

D. J. Sheward, M. Mandolesi, E. Urgard, C. Kim, L. Hanke, L. Perez Vidakovics, A. Pankow, N. L. Smith, X. Castro Dopico, G. M. McInerney, J. M. Coquet, G. Karlsson Hedestam, B. Murrell

A single dose of a VOC-derived RBD protein boost enhances potent neutralizing antibodies against both Wu-Hu-1 and the VOC in previously vaccinated rhesus macaques.

bioRxiv · Apr 3, 2021 · PreprintImmunology

A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo

L. Hanke, H. Das, D. Sheward, L. Perez Vidakovics, E. Urgard, A. Moliner Morro, K. Changil, V. Karl, A. Pankow, N. Smith, B. Porebski, O. Fernandez-Capetillo, E. Sezgin, G. Pedersen, J. M. Coquet, , G. M. McInerney

A bispecific nanobody neutralizes SARS-CoV-2 and its variant B.1.351 by inducing spike trimer-dimers that prevent ACE2 binding.

bioRxiv · Mar 20, 2021Immunology

SARS-CoV-2 protein subunit vaccination elicits potent neutralizing antibody responses

M. Mandolesi, D. J. Sheward, L. Hanke, J. Ma, P. Pushparaj, L. Perez Vidakovics, C. Kim, K. Lore, X. Castro Dopico, J. M. Coquet, G. McInerney, G. B. Karlsson Hedestam, B. Murrell

This study shows that SARS-CoV-2 spike protein subunit vaccines induce strong neutralizing antibodies in mice and macaques, with high titers after a single dose or dose-sparing regimen.

bioRxiv · Jul 31, 2020Immunology