Author

M. Milighetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. Chain· 3 shared A. Chandran· 1 shared A. J. Mentzer· 1 shared A. M. Pesenacker· 1 shared A. Mayer· 1 shared A. McKnight· 1 shared A. Otter· 1 shared A. Semper· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

B. Chain

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Systematic analysis of CDR contacts and sequence constraints between T cell receptor αβ chains.

M. Milighetti, Y. Nagano, J. Henderson, U. Hershberg, A. Tiffeau-Mayer, A.-F. Bitbol, B. Chain

This study systematically analyzes CDR contacts and sequence constraints between TCR αβ chains using TCR structures and mutual information, showing sequence dependencies and co-evolution patterns.

bioRxiv · May 24, 2024 · PreprintImmunology

Treg fitness as a biomarker for disease activity in Juvenile Idiopathic Arthritis

M. H. Attrill, D. Shinko, T. M. Viveiros, M. Milighetti, N. M. Gruijter, B. Jebson, M. Kartawinata, E. C. Rosser, L. R. Wedderburn, CHARMS and JIAP Studies, A. M. Pesenacker

The paper develops a Treg gene and protein signature to predict disease activity in Juvenile Idiopathic Arthritis using machine learning and flow cytometry.

bioRxiv · Apr 24, 2024 · PreprintImmunology

Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection.

M. Milighetti, Y. Peng, C. C. S. Tan, M. Mark, G. Nageswaran, S. Byrne, T. Ronel, T. Peacock, A. Mayer, A. Chandran, J. Rosenheim, M. Wheelan, X. Yao, G. Liu, S. L. Felce, , B. Chain

The paper identifies high frequency naive T cell precursors that drive rapid T cell responses during early SARS-COV-2 and LCMV infections.

bioRxiv · Nov 8, 2022Immunology

Predicting T cell receptor antigen specificity from structural features derived from homology models of receptor-peptide-major histocompatibility complexes.

M. Milighetti, J. Shawe-Taylor, B. Chain

The paper develops a classifier to predict TCR binding using structural features from homology models of TCR-pMHC complexes, achieving comparable performance to sequence-based methods with smaller training sets.

bioRxiv · May 19, 2021Immunology