Author

A. McKnight

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

J. M. Gibbons· 3 shared C. Pade· 2 shared A. Bryan· 1 shared A. Chandran· 1 shared A. Fung· 1 shared A. J. Mentzer· 1 shared A. Mayer· 1 shared A. Nans· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

J. M. Gibbons

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1

S. Griffith, L. Muir, O. Suchanek, J. Hope, C. Pade, J. M. Gibbons, Z. K. Tuong, A. Fung, E. Touizer, C. Rees-Spear, A. Nans, C. Roustan, Y. Alguel, D. Fink, C. Orkin, , L. E. McCoy

The paper isolates a broadly neutralizing HIV-1 antibody from an untreated HIV-1 patient and shows memory B cells remain functional despite viral infection.

bioRxiv · Feb 5, 2024 · PreprintMicrobiology

Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection.

M. Milighetti, Y. Peng, C. C. S. Tan, M. Mark, G. Nageswaran, S. Byrne, T. Ronel, T. Peacock, A. Mayer, A. Chandran, J. Rosenheim, M. Wheelan, X. Yao, G. Liu, S. L. Felce, , B. Chain

The paper identifies high frequency naive T cell precursors that drive rapid T cell responses during early SARS-COV-2 and LCMV infections.

bioRxiv · Nov 8, 2022Immunology

Pneumococcal Evasion of Antibiotics via Metabolic Adaptation During Infection

T. Dao, H. Echlin, A. McKnight, E. Marr, J. Junker, Q. Jia, R. Hayden, J. Rosch

This study shows that S. pneumoniae evades fluoroquinolone antibiotics through metabolic adaptation that reduces reactive oxygen species production, enabling tolerance and fitness restoration.

bioRxiv · Apr 14, 2022 · PreprintMicrobiology

HIV-1 accessory protein Vpr interacts with REAF and mitigates its associated antiviral 1 activity.

J. M. Gibbons, K. M. Marno, R. Pike, W.-y. J. Lee, C. E. Jones, B. W. Ogunkolade, C. Pardieu, A. Bryan, R. M. Fu, G. Warnes, P. A. Rowley, R. D. Sloan, A. McKnight

This paper shows that HIV-1 Vpr interacts with REAF, a macrophage-expressed antiviral factor, and promotes its degradation to enhance HIV replication.

bioRxiv · Oct 30, 2019Microbiology