M. Miyoshi

Myogenic anti-nucleolin aptamer iSN04 inhibits proliferation and promotes differentiation of vascular smooth muscle cells

The paper shows that the anti-nucleolin aptamer iSN04 inhibits vascular smooth muscle cell proliferation and promotes differentiation, suggesting it as a potential therapy for vascular disease.

Anti-nucleolin aptamer, iSN04, inhibits the inflammatory responses in myoblasts by modulating the β-catenin/NF-κB signaling pathway

This study shows that iSN04, an anti-nucleolin aptamer, reduces inflammation in myoblasts by inhibiting the β-catenin/NF-κB pathway.

Identification of a novel osteogenetic oligodeoxynucleotide (osteoDN) that promotes osteoblast differentiation in a TLR9-independent manner

The paper identifies an ODN, iSN40, that promotes osteoblast differentiation and calcification without relying on TLR9.

Clinical evaluation of presepsin considering renal function.

This study recalculates the reference range for presepsin considering renal function, finding it significantly lower than the standard range and correlated with renal biomarkers.