Author

Y. Nihashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

T. Shimosato· 7 shared T. Takaya· 7 shared K. Umezawa· 5 shared S. Shinji· 4 shared H. Kagami· 3 shared S. Nakamura· 2 shared M. Ishioka· 1 shared M. Miyoshi· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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7 shared papersCell Biology

T. Shimosato

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7 papers

Recent·Most cited

Development of the 12-base short dimeric myogenetic oligodeoxynucleotide that induces myogenic differentiation

K. Umezawa, R. Ikeda, T. Sakamoto, Y. Enomoto, Y. Nihashi, S. Shinji, T. Shimosato, H. Kagami, T. Takaya

This paper develops a 12-base myogenetic oligodeoxynucleotide that maintains the myogenic activity of a longer sequence while improving drug efficacy and synthesis cost.

bioRxiv · Mar 14, 2024Cell Biology

Myogenetic oligodeoxynucleotide induces myocardial differentiation of murine pluripotent stem cells

M. Ishioka, Y. Nihashi, Y. Sunagawa, K. Umezawa, T. Shimosato, H. Kagami, T. Morimoto, T. Takaya

This study shows that the myogenetic oligodeoxynucleotide iSN04 induces cardiomyocyte differentiation from murine pluripotent stem cells by modulating Wnt signaling and inhibiting nucleolin.

International Journal of Molecular Sciences · Sep 21, 2023Peer-reviewedCell Biology

Identification of a novel osteogenetic oligodeoxynucleotide (osteoDN) that promotes osteoblast differentiation in a TLR9-independent manner

Y. Nihashi, M. Miyoshi, K. Umezawa, T. Shimosato, T. Takaya

The paper identifies an ODN, iSN40, that promotes osteoblast differentiation and calcification without relying on TLR9.

bioRxiv · Mar 21, 2022Cell Biology

Myogenetic oligodeoxynucleotide restores differentiation and reverses inflammation of myoblasts aggravated by cancer-conditioned medium

Y. Nihashi, M. Yamamoto, T. Shimosato, T. Takaya

This study shows that the oligodeoxynucleotide iSN04 restores myoblast differentiation and reverses inflammation caused by cancer-conditioned medium.

bioRxiv · Nov 17, 2021Cell Biology

Myogenetic oligodeoxynucleotides as anti-nucleolin aptamers inhibit the growth of embryonal rhabdomyosarcoma cells

N. Nohira, S. Shinji, S. Nakamura, Y. Nihashi, T. Shimosato, T. Takaya

This study shows that anti-nucleolin aptamers iSN04 and AS1411 inhibit the growth of embryonal rhabdomyosarcoma cells by targeting nucleolin expression.

bioRxiv · Oct 18, 2021Cell Biology

Myogenetic oligodeoxynucleotide (myoDN) complexed with berberine promotes differentiation of chicken skeletal muscle myoblasts

Y. Nihashi, S. Shinji, K. Umezawa, T. Shimosato, T. Ono, H. Kagami, T. Takaya

This study shows that myogenetic oligodeoxynucleotides (myoDNs) enhance chicken myoblast differentiation, with the iSN04-berberine complex showing increased activity in myotube formation and myogenic gene expression.

bioRxiv · Dec 19, 2020Cell Biology

Identification of the myogenetic oligodeoxynucleotides (myoDNs) that promote differentiation of skeletal muscle myoblasts by targeting nucleolin

S. Shinji, K. Umezawa, Y. Nihashi, S. Nakamura, T. Shimosato, T. Takaya

The paper identifies bacterial-derived oligodeoxynucleotides (myoDNs) that promote skeletal muscle myoblast differentiation by targeting nucleolin.

bioRxiv · Oct 7, 2020Cell Biology