Author

M. Naesens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

A. P. McMahon· 3 shared A. Faivre· 2 shared D. Legouis· 2 shared J. Pugin· 2 shared K. Koppitch· 2 shared S. de Seigneux· 2 shared A. Astorga-Gamaza· 1 shared A. Hertig· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersPathology

A. P. McMahon

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inflammasome Profiling in Human Natural Killer Cells under Pro-inflammatory Stimuli and Solid Organ Transplantation

A. Astorga-Gamaza, I. Muela-Zarzuela, J. M. Suarez-Rivero, A. Varin, M. Naesens, A. Tammaro, J. Kers, J. Lopez-Perez, R. de la Varga-Martinez, A. Mazuecos, B. Lamarthee, M. D. Cordero

This study shows human NK cells can activate inflammasomes in vitro and in transplant patients, with distinct responses in CD56 subsets and sustained activation in renal dysfunction and transplant rejection.

bioRxiv · Apr 17, 2024 · PreprintImmunology

Single-cell profiling in COVID-19 associated acute kidney injury reveals patterns of tubule injury and repair in human

D. Legouis, A. Rinaldi, G. Arnoux, T. Verissimo, J. Scotti-Gerber, A. Faivre, M. Schibler, A. Rinaldi, M. Naesens, K. Koppitch, J. Pugin, A. P. McMahon, S. Moll, S. de Seigneux, P. E. Cippa

This study uses single-nucleus RNA sequencing to analyze kidney tubule injury and repair in COVID-19 patients, identifying cell state transitions and reparative mechanisms.

bioRxiv · Oct 5, 2021Pathology

Impaired renal gluconeogenesis is a major determinant of acute kidney injury associated mortality

D. Legouis, S.-E. Ricksten, A. Faivre, K. Gariani, P. Galichon, L. Berchtold, E. Feraille, K. Koppitch, A. Hertig, P.-Y. Martin, M. Naesens, J. Pugin, A. P. McMahon, P. E. Cippà, S. de Seigneux

This study shows impaired renal gluconeogenesis during AKI contributes to systemic metabolic disturbances and mortality, with thiamine supplementation reducing mortality in critically ill patients.

bioRxiv · Oct 16, 2019Cell Biology

Late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation

P. Cippa, J. Liu, B. Sun, S. Kumar, M. Naesens, A. P. McMahon

The paper identifies a late B lymphocyte response linked to renal dysfunction and fibrosis following kidney injury and transplantation.

bioRxiv · Jun 8, 2018Immunology