Author

A. P. McMahon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 2 Approach:deep learning· 1

Frequent Co-Authors

M. Naesens· 3 shared A. Faivre· 2 shared D. Legouis· 2 shared J. Guo· 2 shared J. Pugin· 2 shared K. Koppitch· 2 shared S. de Seigneux· 2 shared A. D. Kim· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersPathology

M. Naesens

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A genetic model for in vivo proximity labeling of the mammalian secretome

R. Yang, A. S. Meyer, I. A. Droujinine, N. D. Udeshi, Y. Hu, J. Guo, J. A. McMahon, D. K. Carey, C. Xu, Q. Fang, J. Sha, S. Qin, D. Rocco, J. Wohlschlegel, A. Y. Ting, , A. P. McMahon

This paper introduces a genetic mouse model for in vivo proximity labeling of the secretome, revealing organ-specific secretory profiles and serum trafficking.

bioRxiv · Apr 13, 2022Cell Biology

Single-cell profiling in COVID-19 associated acute kidney injury reveals patterns of tubule injury and repair in human

D. Legouis, A. Rinaldi, G. Arnoux, T. Verissimo, J. Scotti-Gerber, A. Faivre, M. Schibler, A. Rinaldi, M. Naesens, K. Koppitch, J. Pugin, A. P. McMahon, S. Moll, S. de Seigneux, P. E. Cippa

This study uses single-nucleus RNA sequencing to analyze kidney tubule injury and repair in COVID-19 patients, identifying cell state transitions and reparative mechanisms.

bioRxiv · Oct 5, 2021Pathology

Spatial Transcriptional Mapping of the Human Nephrogenic Program

N. O. Lindstrom, R. Sealfon, X. Chen, R. Parvez, A. Ransick, G. De Sena Brandine, J. Guo, B. Hill, T. Tran, A. D. Kim, J. Zhou, A. Tadych, A. Watters, A. Wong, E. Lovero, , A. P. McMahon

The paper spatially maps the human nephrogenic program using single-cell RNA sequencing and generates functional gene-networks to identify developmental disease genes and predict new targets.

bioRxiv · Apr 27, 2020Cell Biology

Impaired renal gluconeogenesis is a major determinant of acute kidney injury associated mortality

D. Legouis, S.-E. Ricksten, A. Faivre, K. Gariani, P. Galichon, L. Berchtold, E. Feraille, K. Koppitch, A. Hertig, P.-Y. Martin, M. Naesens, J. Pugin, A. P. McMahon, P. E. Cippà, S. de Seigneux

This study shows impaired renal gluconeogenesis during AKI contributes to systemic metabolic disturbances and mortality, with thiamine supplementation reducing mortality in critically ill patients.

bioRxiv · Oct 16, 2019Cell Biology

Late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation

P. Cippa, J. Liu, B. Sun, S. Kumar, M. Naesens, A. P. McMahon

The paper identifies a late B lymphocyte response linked to renal dysfunction and fibrosis following kidney injury and transplantation.

bioRxiv · Jun 8, 2018Immunology