PPTC7 limits mitophagy through proximal and dynamic interactions with BNIP3 and NIX
L. Wei, M. O. Gok, J. D. Svoboda, M. Forny, J. R. Friedman, N. M. Niemi
This paper shows that PPTC7 limits mitophagy by interacting with BNIP3 and NIX, promoting their proteasomal degradation through dynamic, proximal associations.
bioRxiv · Jan 24, 2024 · PreprintBiochemistry