Author

N. O. Speer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

W. M. Henne· 3 shared E. Reynolds· 2 shared A. Bacle· 1 shared A. Brudnicka· 1 shared A. Kovalenko· 1 shared A. R. Thiam· 1 shared D. Nicastro· 1 shared E. Reetz· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

W. M. Henne

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Author profile →

3 papers

Recent·Most cited

Tld1 is a novel regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation

N. O. Speer, R. J. Braun, E. Reynolds, A. Brudnicka, J. Swanson, W. M. Henne

The paper identifies Tld1 as a regulator of triglyceride lipolysis that specifically targets TG-rich lipid droplets and modulates lipolysis in yeast.

bioRxiv · Mar 7, 2023Cell Biology

Triglyceride lipolysis driven by glucose restriction triggers liquid-crystalline phase transitions and proteome remodeling of lipid droplets

S. Rogers, L. Gui, A. Kovalenko, V. Zoni, M. Carpentier, K. Ramji, K. Ben Mbarek, A. Bacle, P. Fuchs, P. Campomanes, E. Reetz, N. O. Speer, E. Reynolds, A. R. Thiam, S. Vanni, , W. M. Henne

The paper shows glucose restriction induces liquid-crystalline phase transitions in lipid droplets by promoting TG lipolysis, which alters lipid composition and remodels the proteome.

bioRxiv · Apr 15, 2022Cell Biology

ER-localized phosphatidylethanolamine synthase plays a conserved role in lipid droplet formation

M. O. Gok, N. O. Speer, W. M. Henne, J. R. Friedman

The paper identifies ER-localized phosphatidylethanolamine synthase (Psd1) as a novel regulator of lipid droplet formation, showing its conserved role across species.

bioRxiv · Aug 31, 2021Cell Biology